Transcriptional regulation by promoters with enhancer function

authors

  • Spicuglia Salvatore
  • Dao Lan T.M.

keywords

  • CRISPR/Cas9
  • Enhancer
  • Epromoter
  • Promoter
  • Gene regulation
  • Reporter-assay

document type

ART

abstract

Promoters with enhancer activity have been described recently. In this point of view, we will discuss current findings highlighting the commonality of this type of regulatory elements, their genetic and epigenetic characteristics, their potential biological roles in the regulation of gene expression and the underlining molecular mechanisms.

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