• Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.
  • Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.
  • Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

Bioinformatics and genomics of molecular networks

This research axis aims at deciphering the functional organization of the genome, defining the functional role of non coding transcripts, analyzing the molecular interactions at the DNA, RNA or protein level, developing new strategies to integrate heterogeneous information.

 

Genetics and genomics of multifactorial diseases

This research axis aims at identifying genes and mechanisms underlying the complex phenotypes in multifactorial diseases such as haematological malignancies, sepsis, malaria, and cardiomyopathies.

Education

TAGC Members are actively involved in education and propose various theoretical and practical courses related to molecular biology, genetics, genomics, bioinformatics, statistics and informatics.

Attendees range from BSc, MSc, and PhD students to postdoctoral fellows and researchers.

Next Generation Sequencing Facility - TGML

The Transcriptomic and Genomic Marseille-Luminy (TGML) platform is involved in transcriptomic and genomic data production and analysis since 2001.

TAGC is part of Centuri

The Turing Centre for Living Systems (CENTURI) is an interdisciplinary project located in Marseille (France). CENTURI aims at developing an integrated interdisciplinary community, to decipher the complexity of biological systems through the understanding of how biological function emerges from the organization and dynamics of living systems.

Bioinformatics Resources and Biological Platforms

The TAGC members develop and deploy bioinformatics tools, databases and workflows ranging from next generations sequencing data analysis to network analysis.

The TAGC also own platforms for molecular biology, cell culture imaging and animals breeding.

Our goal

Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

News

  1. New Funding - ANR - CE15, Immunologie, Infectiologie et Inflammation

    Christophe Chevillard was one of the Laureat of the Appel à projets générique 2019 - CE15, Immunologie, Infectiologie et Inflammation - « Instrument de financement : Projet de Recherche Collaborative (PRC) »

    Project: Landscardio

    Title: Caractérisation de variations génétiques délétaires associées aux cardiomyopathies

    Coordinator: Christophe  CHEVILLARD

    Time period: 2020-2023

    Abstract:

  2. PhD Thesis defense - Yvon MBOUAMBOUA

     

    Combinaison d’'approches expérimentales et bioinformatiques pour caractériser les interactions entre Plasmodium falciparum et son hôte

    Friday 27th Septembre 2019

    Director: Prof. Jacques VAN HELDEN

    Co-Director: Dr. Francine NTOUMI (Université Marien Ngouabi)

  3. PhD Thesis defense - Saadat HUSSAIN

     

    Etude à grande échelle des éléments répresseurs dans les Lymphocytes T

    Thursay 26th Septembre 2019 at 14:00 - Amphi 12, Bat.B Aix Marseille university, Luminy Campus, Marseille cedex 09

  4. Amidex Postdoctoral positions
  5. Centuri Postdoctoral positions

    The Turing Center for Living System (Centuri) propose two post-doctoral positions on the following topics:

    • Developing graph-based approaches to assemble -omics layers and model regulation of imprinted genes in Prader-Willi syndrome
    • Supervised learning of disease-specific models to predict gene regulatory loci

     

    Deadline for application is April 26th, 2019.

     

  6. Sujets de thèse proposés par le TAGC dans le cadre de l’école doctorale

    Les chercheurs du TAGC proposent 6 sujets de thèse. Les modalités du concours sont indiquées sur le site de l’école doctorale :

    https://ecole-doctorale-62.univ-amu.fr/fr/futur-doctorant/financements/concours-lecole-doctorale.

    Les sujets de thèse sont téléchargeables à partir du site web de l’école doctorale. Les étudiants intéressés sont encouragés à contacter les porteurs (voir coordonnées indiquées sur le sujet téléchargeable sur le site de l’école doctorale).

  7. New funding - A*Midex International

    Laurent Perrin was one of the Laureat of the Amidex International grant with the project Archi-Old-heart

    Subject: A Systems genetic approach of cardiac aging in Drosophila: Elucidating the genetic architecture of cardiac senescence in a model organism.

    Summary:

  8. New funding - A*Midex International

    Christophe Chevillard was one of the Laureat of the A*Midex International grant with the project MITOMUTCHAGAS.

    Subject: Additive effect of pathogenic mutations in mitochondrial proteins and inflammatory cytokines in mitochondrial dysfunction and innate immunity: relevance for Chagas disease cardiomyopathy

    Thematic axis: Heath and life science

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