• Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.
  • Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.
  • Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

Bioinformatics and genomics of molecular networks

This research axis aims at deciphering the functional organization of the genome, defining the functional role of non coding transcripts, analyzing the molecular interactions at the DNA, RNA or protein level, developing new strategies to integrate heterogeneous information.

 

Genetics and genomics of multifactorial diseases

This research axis aims at identifying genes and mechanisms underlying the complex phenotypes in multifactorial diseases such as haematological malignancies, sepsis, malaria, and cardiomyopathies.

Education

TAGC Members are actively involved in education and propose various theoretical and practical courses related to molecular biology, genetics, genomics, bioinformatics, statistics and informatics.

Attendees range from BSc, MSc, and PhD students to postdoctoral fellows and researchers.

Next Generation Sequencing Facility - TGML

The Transcriptomic and Genomic Marseille-Luminy (TGML) platform is involved in transcriptomic and genomic data production and analysis since 2001.

TAGC is part of Centuri

The Turing Centre for Living Systems (CENTURI) is an interdisciplinary project located in Marseille (France). CENTURI aims at developing an integrated interdisciplinary community, to decipher the complexity of biological systems through the understanding of how biological function emerges from the organization and dynamics of living systems.

Bioinformatics Resources and Biological Platforms

The TAGC members develop and deploy bioinformatics tools, databases and workflows ranging from next generations sequencing data analysis to network analysis.

The TAGC also own platforms for molecular biology, cell culture imaging and animals breeding.

Our goal

Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

Events

28 Jun 2019

Internal Seminar - Tom Tran

News

  1. Amidex Postdoctoral positions
  2. Centuri Postdoctoral positions

    The Turing Center for Living System (Centuri) propose two post-doctoral positions on the following topics:

    • Developing graph-based approaches to assemble -omics layers and model regulation of imprinted genes in Prader-Willi syndrome
    • Supervised learning of disease-specific models to predict gene regulatory loci

     

    Deadline for application is April 26th, 2019.

     

  3. Sujets de thèse proposés par le TAGC dans le cadre de l’école doctorale

    Les chercheurs du TAGC proposent 6 sujets de thèse. Les modalités du concours sont indiquées sur le site de l’école doctorale :

    https://ecole-doctorale-62.univ-amu.fr/fr/futur-doctorant/financements/concours-lecole-doctorale.

    Les sujets de thèse sont téléchargeables à partir du site web de l’école doctorale. Les étudiants intéressés sont encouragés à contacter les porteurs (voir coordonnées indiquées sur le sujet téléchargeable sur le site de l’école doctorale).

  4. New funding - A*Midex International

    Laurent Perrin was one of the Laureat of the Amidex International grant with the project Archi-Old-heart

    Subject: A Systems genetic approach of cardiac aging in Drosophila: Elucidating the genetic architecture of cardiac senescence in a model organism.

    Summary:

  5. New funding - A*Midex International

    Christophe Chevillard was one of the Laureat of the A*Midex International grant with the project MITOMUTCHAGAS.

    Subject: Additive effect of pathogenic mutations in mitochondrial proteins and inflammatory cytokines in mitochondrial dysfunction and innate immunity: relevance for Chagas disease cardiomyopathy

    Thematic axis: Heath and life science

  6. Chromatin Meets South - Marseille, July 01-02, 2019

    This 2-day informal meeting is the 9th edition in the conference series «Chromatin Meets South». It is focused on fundamental aspects of chromatin biology and on the latest advances in understanding chromatin structure and function, gene expression and genome integrity. This meeting will bring together leading researchers from the South of France to explore outstanding questions in chromatin-related topics and enable participants to identify new research opportunities and collaborations, and to allow PhD students and post-doc fellows to present their results to a large audience.

  7. New equipment : flow cytometer analyzer and cell sorter

    The institute has just obtained 150 k€ from the PACA Region to equip the cell culture platform of the INSERM-TPR2 building on state of the art flow cytometer analyzer and cell sorter. The application was led by Salvatore Spicuglia along with other researcher from the U1097, U1067, U1072 Inserm units. These equipments will provide new opportunities for the TPR2 units and a large number of regional actors to develop new techniques for functional analysis and sorting of rare cell populations from valuable and/or infected samples.

  8. ENHPATHY, a multidisciplinary consortium

Latest publications