• Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

  • Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

  • Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

Bioinformatics and genomics of molecular networks

This research axis aims at deciphering the functional organization of the genome, defining the functional role of non coding transcripts, analyzing the molecular interactions at the DNA, RNA or protein level, developing new strategies to integrate heterogeneous information.

 

Genetics and genomics of multifactorial diseases

This research axis aims at identifying genes and mechanisms underlying the complex phenotypes in multifactorial diseases such as haematological malignancies, sepsis, malaria, and cardiomyopathies.

Education

TAGC Members are actively involved in education and propose various theoretical and practical courses related to molecular biology, genetics, genomics, bioinformatics, statistics and informatics.

Attendees range from BSc, MSc, and PhD students to postdoctoral fellows and researchers.

Next Generation Sequencing Facility - TGML

The Transcriptomic and Genomic Marseille-Luminy (TGML) platform is involved in transcriptomic and genomic data production and analysis since 2001.

TAGC is part of Centuri

The Turing Centre for Living Systems (CENTURI) is an interdisciplinary project located in Marseille (France). CENTURI aims at developing an integrated interdisciplinary community, to decipher the complexity of biological systems through the understanding of how biological function emerges from the organization and dynamics of living systems.

Bioinformatics Resources and Biological Platforms

The TAGC members develop and deploy bioinformatics tools, databases and workflows ranging from next generations sequencing data analysis to network analysis.

The TAGC also own platforms for molecular biology, cell culture imaging and animals breeding.

Our goal

Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

Events

9 Dec 2022

Internal seminar - Julie Bavais

News

  1. Podcast France Culture - La première cartographie des contacts moléculaires entre l'humain et le SARS-COV-2
  2. A proteome-scale map of the SARS-CoV-2 human contactome

    A international consortium led by the Helmhotz Zentrum in Munich  has identified more than 200 protein interactions between the virus and the human cells.

    Andreas Zanzoni and Christine Brun from TAGC have contributed to the analysis of the contactome map in the context of the RiPCoN project funded by the European Union’s Horizon 2020 Research and Innovation Programme (H2020-SC1-PHE-CORONAVIRUS-2020). 

     

  3. Le TAGC participe à la Fête de la Science 2022

    Titre de l'animation : "Les betes de laboratoire au service de la génétique : les mouches se mettent sur leur 31 !"

    Date : les 15 et 16 octobre

    Lieu : Esplanade de la Marie, 13002 Marseille

    Avec la participation de chercheuses et étudiant et étudiantes en doctorat du TAGC:

    • Matthieu ADJEMOUT
    • Nathalie ARQUIER
    • Katell AUDOUIN
    • Fayrouz HAMMAL
    • Juliette MALFAIT
    • Sandrine MARQUET
    • Lydie PRADEL

     

  4. Soutenance de Thèse - Sébastien Choteau

    Titre de thèse : Exploration des fonctions des petits ORFs (sORFs) dans les monocytes

    Date : Vendredi 9 décembre 2022 à 10:00
    Adresse : Amphithéâtre de l'Hexagone, 163 Avenue de Luminy, Marseille

    Jury

  5. Les Epromoteurs contrôlent les gènes à distance
  6. The TAGC and ABD have obtained funding from the “Plan France Relance”
  7. Broad H3K4me3 domains are hijacked in leukemic cells.
  8. “…Important progress in our present knowledge of interaction networks and of the interactome are essential to understand how gene functions and regulations are integrated at the level of an organism.” Bernard Jacq (1950-2022)

    Bernard Jacq (1950-2022)

    Directeur de Recherches CNRS

    A l’international, il fut celui qui en 1999, pensa et conceptualisa l’ensemble des interactions moléculaires et génétiques d’un organisme comme un réseau qui nous informerait sur le lien entre génotype et phénotype, donnant ainsi son nom à l’interactome et au champ thématique correspondant, l’interactomique.  

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