This research axis aims at deciphering the functional organization of the genome, defining the functional role of non coding transcripts, analyzing the molecular interactions at the DNA, RNA or protein level, developing new strategies to integrate heterogeneous information.
This research axis aims at identifying genes and mechanisms underlying the complex phenotypes in multifactorial diseases such as haematological malignancies, sepsis, malaria, and cardiomyopathies.
TAGC Members are actively involved in education and propose various theoretical and practical courses related to molecular biology, genetics, genomics, bioinformatics, statistics and informatics.
Attendees range from BSc, MSc, and PhD students to postdoctoral fellows and researchers.
The Transcriptomic and Genomic Marseille-Luminy (TGML) platform is involved in transcriptomic and genomic data production and analysis since 2001.
The TAGC members develop and deploy bioinformatics tools, databases and workflows ranging from next generations sequencing data analysis to network analysis.
The TAGC also own platforms for molecular biology, cell culture imaging and animals breeding.
Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.
The TAGC has changed its name!
TAGC now stands for "Theories and Approaches of Genomic Complexity".
In 2018, Marseille will receive JOBIM (Journées Ouvertes pour la Biologie, l’Informatique et les Mathématiques) at the Palais du Pharo, from July 3rd to July 6th, 2018. JOBIM is the yearly conference of the French Society of Bioinformatics (SFBI). By promoting the exchanges between biologists, mathematicians, physicists and computer scientists, JOBIM constitutes the major event of the French bioinformatics community.
ReMap is an integrative analysis of transcriptional regulators ChIP-seq experiments from both Public and Encode datasets. The ReMap atlas consits of 80 million peaks from 485 transcription factors (TFs), transcription coactivators (TCAs) and chromatin-remodeling factors (CRFs) http://remap.cisreg.eu/
The Turing Centre deciphers the complexity and the dynamics of living systems. CENTURI federates a growing community of biologists, physicists, mathematicians, computer scientists and engineers. Numerous teaching and research institutes, among which the TAGC, are involved in the project. Interdisciplinarity is the core principle of the Turing Centre and is central to its activity in research, education and technology.