ESCANDELL Amélie

Telephone
+33 (0)4 91 82 87 00
linkedin
Status
Fix-term research staff
Engineer
Diseases, phenotypes & models
Malaria
Cells
Human
in vitro
Research axes
A.1 - Bioinformatics and Genomics of Molecular Networks
A.1.2 - Discovery and functional dissection of Regulatory Elements
A.2 - Genetics and Genomics of Multifactioral Diseases
A.2.2 - Characterization of altered cellular functions in disease states

Scientific and administrative responsibilities

Member of the RPS (Risques Psycho-Sociaux) team

Research interests

My research focuses on the functioning of cis-regulatory elements. To better understand their role, I use a combination of molecular and cellular biology approaches as well as high-throughput techniques. In particular, I exploit MPRA and STARR-seq technologies to map and quantify the activity of regulatory sequences on a large scale. I also integrate CRISPR-based approaches to modulate these elements and analyze their functional impact. My aim is to decipher the mechanisms by which these regions influence gene expression and their potential role in biological and pathological processes.

Collaborations

Internal to the laboratory :

- Sandrine MARQUET
- Salvatore SPICUGLIA

External references

https://orcid.org/0009-0007-5803-1407