• Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

  • Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

  • Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

Bioinformatics and genomics of molecular networks

This research axis aims at deciphering the functional organization of the genome, defining the functional role of non coding transcripts, analyzing the molecular interactions at the DNA, RNA or protein level, developing new strategies to integrate heterogeneous information.

 

Genetics and genomics of multifactorial diseases

This research axis aims at identifying genes and mechanisms underlying the complex phenotypes in multifactorial diseases such as haematological malignancies, sepsis, malaria, and cardiomyopathies.

Education

TAGC Members are actively involved in education and propose various theoretical and practical courses related to molecular biology, genetics, genomics, bioinformatics, statistics and informatics.

Attendees range from BSc, MSc, and PhD students to postdoctoral fellows and researchers.

Next Generation Sequencing Facility - TGML

The Transcriptomic and Genomic Marseille-Luminy (TGML) platform is involved in transcriptomic and genomic data production and analysis since 2001.

TAGC is part of Centuri

The Turing Centre for Living Systems (CENTURI) is an interdisciplinary project located in Marseille (France). CENTURI aims at developing an integrated interdisciplinary community, to decipher the complexity of biological systems through the understanding of how biological function emerges from the organization and dynamics of living systems.

Bioinformatics Resources and Biological Platforms

The TAGC members develop and deploy bioinformatics tools, databases and workflows ranging from next generations sequencing data analysis to network analysis.

The TAGC also own platforms for molecular biology, cell culture imaging and animals breeding.

Our goal

Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.

Events

2 Dec 2020

Internal Seminar - Nori Sadouni - Nathalie Arquier

News

  1. PHD THESIS DEFENSE - David Santiago Algarra

    Title: Dissection of coordinated interferon response by promoter elements with enhancer activity

    Date: Thursday, December 10, 2020, 2pm 

    Location: Hexagone Amphitheater

    Jury: Susanne Mandrup, Gioacchinao Natoli, Sandrine Sarrazin, Jean-Christophe Andrau, Salvatore Spicuglia

     

  2. Salvatore Spicuglia obtains two new fundings on G4 DNA structures

    Two fundings (ANR and PLBio-INCA) have been obtained to work on the role of G-quadruplexes in transcription regulation and its impact in Cancer. The projects involve a collaboration between Salvatore Spicuglia (TAGC), Jean Christophe Andrau (IGMM, Montpellier) and Jean-Louis Mergny (LOB, Paris).

  3. Special issue of International Journal of Molecular Sciences

    Christophe Chevillard is editor of a special issue of International Journal of Molecular Sciences (ISSN 1422-0067) on "Genetic Analysis, Pathogenic Process Deciphering, Drug Development in Parasitic Diseases".

    Interests: Cardiac & Cardiovascular Systems; Parasitology; Genomics; Schistosomiasis; human susceptibility to infection and severe disease.

    Deadline for manuscript submissions: February 28th 2021.

     

  4. The TAGC presents the job of Bioinformatician for "L'Explorateur de Métiers ®".
  5. A new EU research project on COVID-19

    TAGC is a partner of the newly awarded RiPCoN project "Rapid interaction profiling of 2019 nCoV for network based deep drug repurpose learning" that started on April 1st, 2020.

    This 3-years project led the Helmholtz Zentrum, Munchen, Germany (Prof. Falter-Braun), to which participates the IRB, Barcelona, Spain (Prof. Aloy), and TAGC (Drs. C. Brun/A. Zanzoni) aims at the identification of approved drugs that can be repurposed for the treatment of SARS-CoV-2 using interactome-profiling and deep-learning.

  6. EnhPathy ITN H2020 Ph.D. call will start on March 15th, 2020

    We are happy to announce that our EnhPathy ITN H2020 Ph.D. call will start on March 15th, 2020. EnhPathy will be recruiting 15 PhD students to start their training program within the September-December 2020 period.

     

Latest publications