The Transcriptomic and Genomic Marseille-Luminy (TGML) platform is involved in transcriptomic and genomic data production and analysis since 2001.
This research axis aims at deciphering the functional organization of the genome, defining the functional role of non coding transcripts, analyzing the molecular interactions at the DNA, RNA or protein level, developing new strategies to integrate heterogeneous information.
This research axis aims at identifying genes and mechanisms underlying the complex phenotypes in multifactorial diseases such as haematological malignancies, sepsis, malaria, and cardiomyopathies.
TAGC Members are actively involved in education and propose various theoretical and practical courses related to molecular biology, genetics, genomics, bioinformatics, statistics and informatics.
Attendees range from BSc, MSc, and PhD students to postdoctoral fellows and researchers.
The Transcriptomic and Genomic Marseille-Luminy (TGML) platform is involved in transcriptomic and genomic data production and analysis since 2001.
The Turing Centre for Living Systems (CENTURI) is an interdisciplinary project located in Marseille (France). CENTURI aims at developing an integrated interdisciplinary community, to decipher the complexity of biological systems through the understanding of how biological function emerges from the organization and dynamics of living systems.
The TAGC members develop and deploy bioinformatics tools, databases and workflows ranging from next generations sequencing data analysis to network analysis.
The TAGC also own platforms for molecular biology, cell culture imaging and animals breeding.
Understanding biological complexity, from genotype to phenotype, with interdisciplinary approaches.
TAGC congratulates Bruno Pouvelle on his promotion to grade "Hors Classe" Research Engineer, in recognition of his involvement in research.
TAGC congratulates Frédéric Gallardo on his promotion to Assistant Engineer.
This is a well-deserved reward for his work and his constant involvement in the laboratory.
IDENTIFICATION ET CARACTERISATIONS FONCTIONNELLES DE VARIANTS GENETIQUES ASSOCIES AUX CARDIOPATHIES
Tuesday December 19th at 1:30 pm
Auditorium - Hexagone 172 Av. de Luminy, 13009 Marseille
Jury :
Mme Frédérique MAGDINIER - Présidente
Mme Véronique PAQUIS-FLUCKLINGER Rapportrice
M. Jean-Jacques SCHOTT - Rapporteur
Mme Alice CARRIER - Examinatrice
M. Vincent PROCACCIO - Examinateur
M. Christophe CHEVILLARD - Directeur de thèse
ETUDE DU PROCESSUS PATHOGENIQUE ASSOCIE A LA MALADIE DE CHAGAS A L'AIDE D'ANALYSES MULTI-OMIQUES
Monday December 11th at 9:00 am
Auditorium - Hexagone 172 Av. de Luminy, 13009 Marseille
Jury :
M. Philippe NAQUET - Président
M. Carl HERRMANN - Rapporteur
M. Adbellah TEBANI - Rapporteur
Mme Laura CANTINI - Examinateur
Mme Anaïs BAUDOT – invitée
M. Christophe CHEVILLARD - Directeur de thèse
M. Lionel SPINELLI - CoDirecteur de thèse
In order to facilitate research on Chagas disease, a manual curation of all articles corresponding to “Chagas disease” referenced on PubMed has been carried out.
Brochet, Pauline, Jean-Christophe Mouren, Laurent Hannouche, Fabrice Lopez, Benoit Ballester, Edecio Cunha-Neto, Lionel Spinelli, and Christophe Chevillard. “ChagasDB: 80 Years of Publicly Available Data on the Molecular Host Response to Trypanosoma Cruzi Infection in a Single Database.” Database 2023 (May 26, 2023): baad037. https://doi.org/10.1093/database/baad037.
Pierre de Langen, Benoit Ballester et al. at TAGC have published a groundbreaking study on intergenic transcription in both normal tissues and cancer samples, unveiling a comprehensive RNAPII atlas:
Characterizing intergenic transcription at RNA polymerase II binding sites in normal and cancer tissues
Open Access. Published:September 29, 2023. DOI:https://doi.org/10.1016/j.xgen.2023.100411
Summary
After the success of the first meeting in Santander (October 2021), we are pleased to announce that registration is now open for the second edition of the EMBO Workshop "Enhanceropathies: Understanding enhancer function to understand human disease" to be held in Marseille from October 17th to 20th, 2023.
We have an amazing speaker line-up and great opportunities for networking !
Interested in attending? Visit the website
Register and submit your abstract by 15 August 2023
A 3-years Human Frontier Research Grant has been obtained by Anne-Ruxandra Carvunis (Pittsburg University, USA), Erich Bornberg-Bauer (University of Münster, Germany) and Christine Brun (TAGC, France) to investigate how the products of De Novo genes evolve to adapt to the interaction network.