BALLESTER Benoit

My research focuses on the analysis of non-coding regions of the human genome using high-throughput sequencing data such as (ChIP-seq, RNA-seq, DNase-seq, ATAC-seq, etc...). I am interested in understanding how the so called non-coding genome play a central role in gene regulation. This previously "junk-dna" is now seen as playing a key and complex role in the regulation of our genome.

How those yet un-annotated regulatory elements can shape the expression and the dynamics of our genomes is the main goal of my work. To address that we first created the ReMap ressource, a catalogue of regulatory elements by integrating thousands of public TF ChIP-seq experiment. This allow us to observe a complex landscape of regulatory elements (Enhancers/CRMs) in the human genome.

ReMap: https://remap.univ-amu.fr/