Our research project is structured around two main axes: "Bioinformatics and Genomics of Molecular Networks" and "Genetics and Genomics of Multifactorial Diseases". 

The first axis focuses on unraveling the functional organization of the genome, characterizing the roles of non-coding RNAs, analyzing molecular interaction networks (DNA, RNA, proteins) through genomics and bioinformatics, and developing novel strategies to integrate heterogeneous biological data into predictive theoretical models. This axis also investigates the impact of genomic variations on gene expression and molecular networks.

The second axis aims to characterize genetic, transcriptomic, epigenomic, and proteomic profiles associated with conditions such as malignant hemopathies, sepsis, malaria, and cardiomyopathies. Researchers seek to identify regulatory elements and molecular networks disrupted by these pathologies, as well as to discover biomarkers and therapeutic targets for their treatment.

Composition of the 2 axes in topics

The concepts and methodologies developed are synergistically applied across both axes and are made accessible to the scientific community.