An Expression Quantitative Trait Locus of Fc Gamma Receptor Genes is Associated with Anti-Malarial IgG Responses and Infection Levels in Burkinabe Families Running Title: Association of rs1771575 with Malaria
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authors
keywords
- Fc Gamma Receptors
- Plasmodium falciparum immunization
- FCGR Expression Quantitative Trait Locus
- FCGR gene polymorphism
- Malaria-blood infectious levels
document type
ARTabstract
This study identifies the non-coding variant rs1771575 in the FCGR gene cluster as a key marker for IgG levels and malaria infection in children. It highlights the role of regulatory and coding variants in shaping immune responses to Plasmodium falciparum.
