Laboratory Director for the coming term (2024-2029).
Member of the Inserm Scientific Advisory Board (appointed since 2022).
Member of the Scientific Advisory Board of the Marseille Institute for Rare Diseases (MarMaRa) (since 2020).
Member of the GOLD transverse program launched by Inserm dealing with genomic variability in health and disease (since 2019).

Executive board members:
Frontiers in Immunology
World Journal of Clinical Infectious Diseases (WJCID)
World Journal of Medical Genetics (WJMG)
Cells

Ad hoc Reviewer for the Journals:
Plos Genetics, Plos Pathogen, Plos Neglected Tropical Disease, Frontiers in immunology, International Journal of Molecular Sciences, Plos one, Human Genetics, Clinical Infectious Diseases, Journal of Infectious Diseases, Circulation, Genes and Immunity, Infection Genetics and Evolution, Mediators of Inflammation.

Expert for funding applications from the following institutions:
NIH (USA),
ANR,
Pasteur Institute

Research interests

Building on my expertise described above, since 2010 my research project has been using OMIC approaches to study the pathogenic processes associated with chronic dilated cardiomyopathies associated with Chagas disease (infection by Trypanosoma cruzi). These cardiomyopathies represent the main cause of morbidity and mortality in Latin America.
We hypothesized that the expression or regulation of certain relevant genes and proteins in myocardial tissue would underlie the pathogenic process. We therefore decided to set up an ambitious program to dissect the pathogenic process, but also to identify markers for diagnosis and prognosis.

Setting up an international consortium.
Recruit the largest possible cohort of patients and asymptomatic individuals. Set up cardiac tissue collection.
Elucidate the pathogenic process involved in Chagas disease.
Identify highly pathogenic common or rare variants associated with the disease.
Set up genome-wide studies.
Exome sequencing in multi-case families.
Identification of genetic variants associated with chagasic cardiomyopathies.
Study of the functional impact of these variants.
Identification of new drugs to restore optimal mitochondrial function.

Teaching

Every year, I teach several courses in France and abroad.
Four hours in M2 Human Pathology: Genomics and Health module, Aix-Marseille University.
Four hours in M1 Human Pathology: Physiopathology of infectious diseases module, Aix-Marseille University.
Four hours in M1 Master Immunology, Aix-Marseille University.
Twenty-five hours at the University of Sao Paulo.

Supervision of staff and students

Supervision of post-docs
Frade Amanda Farage, Nunes Joao Paulo

Supervision of doctoral students
Guerin Hélléa, Andrieux Pauline, Brochet Pauline, Laugier Laurie, Isnard Amandine, Arnaud Violaine, Eboumbou Carole

Student supervision (up to Master's level)
Nicolas Schleinitz, Sandrine Henri, Romain Roncagalli, Nasrueldin Elwalli, Nadia Haribou Zoubert, Adil Merghani, Carole Eboumbou Moukoko, Bouréma Kouriba, Béatrice Bréart, Nicolas Crapoulet, Stephane Jaureguiberry, Violaine Arnaud, Hongbin He, Amandine Isnard, Agnes Llored, Hélène Giniaux, Laurie Laugier, Sophie Sivera, Maryem Ourhache, Emy Pousardin, Pauline Brochet, Carlos Bathich, Romain Sprynski, Serena Renoliet, Leopoldine Lecerf, Roni Sleiman, Clarisse Roger, Hellea Guerin

Collaborations

French Collaborators
Dr. Laurent Abel INSERM U980, Paris
Dr. Aurélie Cobat INSERM U980, Paris
Pr. Vincent Procaccio, CHU d'Angers, Angers
Dr. Julien Barc, institut du thorax, Nantes
Dr. Anaïs Beaudot MMG, Marseille

Brazilian Collaborators
InCor - Heart Institute (InCor), São Paulo, SP-Brazil
Pr. Jorge Kalil, Pr. Edecio Cunha-Neto, Dr. Priscila Teixeira, Dr . Ludmila Ferreira, Dr. Luciana Nogueira, Dr. Frederico Ferreira, Dr. Eliane Mairena, Dr. Andreia Kuramoto, Dr. Monique Baron, Dr. Alexandre Pereira, Dr. Edimar Bocchi, Dr. Barbara Ianni Dr. Ronaldo Barros, Dr. Alfredo Fiorelli, Dr. Noedir Stolf, Dr. Luiz Benvenuti

Federal University of the Triângulo Mineiro, Uberaba, MG-Brazil
Pr. Virmondes Rodrigues Jr, Dr. Cristina Wide Pissetti, Dr. Ariana Borges, Pr. Dalmo Correa, Dr. Maurico Liaguno

Dante Pazzanese Cardiology Institute, São Paulo, SP-Brazil
Dr. Mario Hirata, Dr. Marcelo Sampaio, Dr. Abílio Fragata, Dr. Bruno Saba, Dr. Lin Hui Tzu Wang

School of Medicine of Ribeirão Preto, Ribeirão Preto, SP-Brazil
Dr. Eduardo Donadi, Dr. Fabricio Dias, Dr. Andre Schmidt, Dr. Jose Marin-Neto, Dr. Fabricio Dias

Spanish Collaborators
Instituto de Parasitología y Biomedicina López Neyra, Granada, Spain
Pr. Javier Martin, Dr. Marialbert Acosta Herrera, Dr. Desiré Casares-Marfil

Funding

Academic honors and awards:
Inserm (international research program) coordinator 2023-2027
CAPES/COFECUB coordinator 2023-2026
FAPESP (Fundação de Amparo à Pesquisa do Estado de São Paulo) partner 2022-2027
ANR landscardio coordinator 2019-2023
FAPESP partner 2020-2022
A*MIDEX coordinator 2019-2021
ANR Br-Fr-Chagas coordinator 2014-2017
CNPQ partner 2014-2017
ARCUS PACA BRAZIL coordinator 2012-2016
USP/COFECUB coordinator 2011-2014

External references

ORCID: https://orcid.org/0000-0002-5269-8813

ResearchID: A-7087-2015

publons: https://publons.com/researcher/1608268/christophe-chevillard

Author publications